Búsqueda | Biblioteca Virtual en Salud

1.

Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid.

Drieu, Antoine; Du, Siling; Storck, Steffen E; Rustenhoven, Justin; Papadopoulos, Zachary; Dykstra, Taitea; Zhong, Fenghe; Kim, Kyungdeok; Blackburn, Susan; Mamuladze, Tornike; Harari, Oscar; Karch, Celeste M; Bateman, Randall J; Perrin, Richard; Farlow, Martin; Chhatwal, Jasmeer; Hu, Song; Randolph, Gwendalyn J; Smirnov, Igor; Kipnis, Jonathan.

Nature ; 611(7936): 585-593, 2022 Nov.

Artículo Inglés | MEDLINE | ID: mdl-36352225

2.

Lecanemab in Early Alzheimer's Disease.

van Dyck, Christopher H; Swanson, Chad J; Aisen, Paul; Bateman, Randall J; Chen, Christopher; Gee, Michelle; Kanekiyo, Michio; Li, David; Reyderman, Larisa; Cohen, Sharon; Froelich, Lutz; Katayama, Sadao; Sabbagh, Marwan; Vellas, Bruno; Watson, David; Dhadda, Shobha; Irizarry, Michael; Kramer, Lynn D; Iwatsubo, Takeshi.

N Engl J Med ; 388(1): 9-21, 2023 01 05.

Artículo Inglés | MEDLINE | ID: mdl-36449413

3.

Two Phase 3 Trials of Gantenerumab in Early Alzheimer's Disease.

Bateman, Randall J; Smith, Janice; Donohue, Michael C; Delmar, Paul; Abbas, Rachid; Salloway, Stephen; Wojtowicz, Jakub; Blennow, Kaj; Bittner, Tobias; Black, Sandra E; Klein, Gregory; Boada, Mercè; Grimmer, Timo; Tamaoka, Akira; Perry, Richard J; Turner, R Scott; Watson, David; Woodward, Michael; Thanasopoulou, Angeliki; Lane, Christopher; Baudler, Monika; Fox, Nick C; Cummings, Jeffrey L; Fontoura, Paulo; Doody, Rachelle S.

N Engl J Med ; 389(20): 1862-1876, 2023 Nov 16.

Artículo Inglés | MEDLINE | ID: mdl-37966285

4.

Timing of Biomarker Changes in Sporadic Alzheimer's Disease in Estimated Years from Symptom Onset.

Li, Yan; Yen, Daniel; Hendrix, Rachel D; Gordon, Brian A; Dlamini, Sibonginkhosi; Barthélemy, Nicolas R; Aschenbrenner, Andrew J; Henson, Rachel L; Herries, Elizabeth M; Volluz, Katherine; Kirmess, Kristopher; Eastwood, Stephanie; Meyer, Matthew; Heller, Maren; Jarrett, Lea; McDade, Eric; Holtzman, David M; Benzinger, Tammie L S; Morris, John C; Bateman, Randall J; Xiong, Chengjie; Schindler, Suzanne E.

Ann Neurol ; 95(5): 951-965, 2024 May.

Artículo Inglés | MEDLINE | ID: mdl-38400792

5.

Suvorexant Acutely Decreases Tau Phosphorylation and Aß in the Human CNS.

Lucey, Brendan P; Liu, Haiyan; Toedebusch, Cristina D; Freund, David; Redrick, Tiara; Chahin, Samir L; Mawuenyega, Kwasi G; Bollinger, James G; Ovod, Vitaliy; Barthélemy, Nicolas R; Bateman, Randall J.

Ann Neurol ; 94(1): 27-40, 2023 07.

Artículo Inglés | MEDLINE | ID: mdl-36897120

6.

Change in Cerebrospinal Fluid Tau Microtubule Binding Region Detects Symptom Onset, Cognitive Decline, Tangles, and Atrophy in Dominantly Inherited Alzheimer's Disease.

Horie, Kanta; Li, Yan; Barthélemy, Nicolas R; Gordon, Brian; Hassenstab, Jason; Benzinger, Tammie L S; Fagan, Anne M; Morris, John C; Karch, Celeste M; Xiong, Chengjie; Allegri, Ricardo; Mendez, Patricio Chrem; Ikeuchi, Takeshi; Kasuga, Kensaku; Noble, James; Farlow, Martin; Chhatwal, Jasmeer; Day, Gregory; Schofield, Peter R; Masters, Colin L; Levin, Johannes; Jucker, Mathias; Lee, Jae-Hong; Roh, Jee Hoon; Sato, Chihiro; Sachdev, Pallavi; Koyama, Akihiko; Reyderman, Larisa; Bateman, Randall J; McDade, Eric.

Ann Neurol ; 93(6): 1158-1172, 2023 06.

Artículo Inglés | MEDLINE | ID: mdl-36843330

7.

Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer's disease.

Janelidze, Shorena; Bali, Divya; Ashton, Nicholas J; Barthélemy, Nicolas R; Vanbrabant, Jeroen; Stoops, Erik; Vanmechelen, Eugeen; He, Yingxin; Dolado, Anna Orduña; Triana-Baltzer, Gallen; Pontecorvo, Michael J; Zetterberg, Henrik; Kolb, Hartmuth; Vandijck, Manu; Blennow, Kaj; Bateman, Randall J; Hansson, Oskar.

Brain ; 146(4): 1592-1601, 2023 04 19.

Artículo Inglés | MEDLINE | ID: mdl-36087307

8.

Clinical validation of the PrecivityAD2 blood test: A mass spectrometry-based test with algorithm combining %p-tau217 and Aß42/40 ratio to identify presence of brain amyloid.

Meyer, Matthew R; Kirmess, Kristopher M; Eastwood, Stephanie; Wente-Roth, Traci L; Irvin, Faith; Holubasch, Mary S; Venkatesh, Venky; Fogelman, Ilana; Monane, Mark; Hanna, Lucy; Rabinovici, Gil D; Siegel, Barry A; Whitmer, Rachel A; Apgar, Charles; Bateman, Randall J; Holtzman, David M; Irizarry, Michael; Verbel, David; Sachdev, Pallavi; Ito, Satoshi; Contois, John; Yarasheski, Kevin E; Braunstein, Joel B; Verghese, Philip B; West, Tim.

Alzheimers Dement ; 2024 Mar 16.

Artículo Inglés | MEDLINE | ID: mdl-38491912

9.

Examining amyloid reduction as a surrogate endpoint through latent class analysis using clinical trial data for dominantly inherited Alzheimer's disease.

Wang, Guoqiao; Li, Yan; Xiong, Chengjie; Benzinger, Tammie L S; Gordon, Brian A; Hassenstab, Jason; Aschenbrenner, Andrew J; McDade, Eric; Clifford, David B; Libre-Guerra, Jorge J; Shi, Xinyu; Mummery, Catherine J; van Dyck, Christopher H; Lah, James J; Honig, Lawrence S; Day, Gregg; Ringman, John M; Brooks, William S; Fox, Nick C; Suzuki, Kazushi; Levin, Johannes; Jucker, Mathias; Delmar, Paul; Bittner, Tobias; Bateman, Randall J.

Alzheimers Dement ; 20(4): 2698-2706, 2024 Apr.

Artículo Inglés | MEDLINE | ID: mdl-38400532

10.

Investigation of sex differences in mutation carriers of the Dominantly Inherited Alzheimer Network.

Wagemann, Olivia; Li, Yan; Hassenstab, Jason; Aschenbrenner, Andrew J; McKay, Nicole S; Gordon, Brian A; Benzinger, Tammie L S; Xiong, Chengjie; Cruchaga, Carlos; Renton, Alan E; Perrin, Richard J; Berman, Sarah B; Chhatwal, Jasmeer P; Farlow, Martin R; Day, Gregory S; Ikeuchi, Takeshi; Jucker, Mathias; Lopera, Francisco; Mori, Hiroshi; Noble, James M; Sánchez-Valle, Raquel; Schofield, Peter R; Morris, John C; Daniels, Alisha; Levin, Johannes; Bateman, Randall J; McDade, Eric; Llibre-Guerra, Jorge J.

Alzheimers Dement ; 20(1): 47-62, 2024 Jan.

Artículo Inglés | MEDLINE | ID: mdl-37740921

11.

α-Synuclein seed amplification assay detects Lewy body co-pathology in autosomal dominant Alzheimer's disease late in the disease course and dependent on Lewy pathology burden.

Levin, Johannes; Baiardi, Simone; Quadalti, Corinne; Rossi, Marcello; Mammana, Angela; Vöglein, Jonathan; Bernhardt, Alexander; Perrin, Richard J; Jucker, Mathias; Preische, Oliver; Hofmann, Anna; Höglinger, Günter U; Cairns, Nigel J; Franklin, Erin E; Chrem, Patricio; Cruchaga, Carlos; Berman, Sarah B; Chhatwal, Jasmeer P; Daniels, Alisha; Day, Gregory S; Ryan, Natalie S; Goate, Alison M; Gordon, Brian A; Huey, Edward D; Ibanez, Laura; Karch, Celeste M; Lee, Jae-Hong; Llibre-Guerra, Jorge; Lopera, Francisco; Masters, Colin L; Morris, John C; Noble, James M; Renton, Alan E; Roh, Jee Hoon; Frosch, Matthew P; Keene, C Dirk; McLean, Catriona; Sanchez-Valle, Raquel; Schofield, Peter R; Supnet-Bell, Charlene; Xiong, Chengjie; Giese, Armin; Hansson, Oskar; Bateman, Randall J; McDade, Eric; Parchi, Piero.

Alzheimers Dement ; 2024 Apr 26.

Artículo Inglés | MEDLINE | ID: mdl-38666355

12.

T1 and FLAIR signal intensities are related to tau pathology in dominantly inherited Alzheimer disease.

Rahmani, Farzaneh; Brier, Matthew R; Gordon, Brian A; McKay, Nicole; Flores, Shaney; Keefe, Sarah; Hornbeck, Russ; Ances, Beau; Joseph-Mathurin, Nelly; Xiong, Chengjie; Wang, Guoqiao; Raji, Cyrus A; Libre-Guerra, Jorge J; Perrin, Richard J; McDade, Eric; Daniels, Alisha; Karch, Celeste; Day, Gregory S; Brickman, Adam M; Fulham, Michael; Jack, Clifford R; la La Fougère, Christian; Reischl, Gerald; Schofield, Peter R; Oh, Hwamee; Levin, Johannes; Vöglein, Jonathan; Cash, David M; Yakushev, Igor; Ikeuchi, Takeshi; Klunk, William E; Morris, John C; Bateman, Randall J; Benzinger, Tammie L S.

Hum Brain Mapp ; 44(18): 6375-6387, 2023 Dec 15.

Artículo Inglés | MEDLINE | ID: mdl-37867465

13.

Progressive White Matter Injury in Preclinical Dutch Cerebral Amyloid Angiopathy.

Shirzadi, Zahra; Yau, Wai-Ying W; Schultz, Stephanie A; Schultz, Aaron P; Scott, Matthew R; Goubran, Maged; Mojiri-Forooshani, Parisa; Joseph-Mathurin, Nelly; Kantarci, Kejal; Preboske, Greg; Wermer, Marieke J H; Jack, Clifford; Benzinger, Tammie; Taddei, Kevin; Sohrabi, Hamid R; Sperling, Reisa A; Johnson, Keith A; Bateman, Randall J; Martins, Ralph N; Greenberg, Steven M; Chhatwal, Jasmeer P.

Ann Neurol ; 92(3): 358-363, 2022 09.

Artículo Inglés | MEDLINE | ID: mdl-35670654

14.

Apolipoprotein E O-glycosylation is associated with amyloid plaques and APOE genotype.

Lawler, Paige E; Bollinger, James G; Schindler, Suzanne E; Hodge, Cynthia R; Iglesias, Nicolas J; Krishnan, Vishal; Coulton, John B; Li, Yan; Holtzman, David M; Bateman, Randall J.

Anal Biochem ; 672: 115156, 2023 07 01.

Artículo Inglés | MEDLINE | ID: mdl-37072097

15.

Unsupervised high-frequency smartphone-based cognitive assessments are reliable, valid, and feasible in older adults at risk for Alzheimer's disease.

Nicosia, Jessica; Aschenbrenner, Andrew J; Balota, David A; Sliwinski, Martin J; Tahan, Marisol; Adams, Sarah; Stout, Sarah S; Wilks, Hannah; Gordon, Brian A; Benzinger, Tammie L S; Fagan, Anne M; Xiong, Chengjie; Bateman, Randall J; Morris, John C; Hassenstab, Jason.

J Int Neuropsychol Soc ; 29(5): 459-471, 2023 06.

Artículo Inglés | MEDLINE | ID: mdl-36062528

16.

Accelerated longitudinal changes and ordering of Alzheimer disease biomarkers across the adult lifespan.

Luo, Jingqin; Agboola, Folasade; Grant, Elizabeth; Morris, John C; Masters, Colin L; Albert, Marilyn S; Johnson, Sterling C; McDade, Eric M; Fagan, Anne M; Benzinger, Tammie L S; Hassenstab, Jason; Bateman, Randall J; Perrin, Richard J; Wang, Guoqiao; Li, Yan; Gordon, Brian; Cruchaga, Carlos; Day, Gregory S; Levin, Johannes; Vöglein, Jonathan; Ikeuchi, Takeshi; Suzuki, Kazushi; Allegri, Ricardo F; Xiong, Chengjie.

Brain ; 145(12): 4459-4473, 2022 12 19.

Artículo Inglés | MEDLINE | ID: mdl-35925685

17.

Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology.

Morris, John C; Weiner, Michael; Xiong, Chengjie; Beckett, Laurel; Coble, Dean; Saito, Naomi; Aisen, Paul S; Allegri, Ricardo; Benzinger, Tammie L S; Berman, Sarah B; Cairns, Nigel J; Carrillo, Maria C; Chui, Helena C; Chhatwal, Jasmeer P; Cruchaga, Carlos; Fagan, Anne M; Farlow, Martin; Fox, Nick C; Ghetti, Bernardino; Goate, Alison M; Gordon, Brian A; Graff-Radford, Neill; Day, Gregory S; Hassenstab, Jason; Ikeuchi, Takeshi; Jack, Clifford R; Jagust, William J; Jucker, Mathias; Levin, Johannes; Massoumzadeh, Parinaz; Masters, Colin L; Martins, Ralph; McDade, Eric; Mori, Hiroshi; Noble, James M; Petersen, Ronald C; Ringman, John M; Salloway, Stephen; Saykin, Andrew J; Schofield, Peter R; Shaw, Leslie M; Toga, Arthur W; Trojanowski, John Q; Vöglein, Jonathan; Weninger, Stacie; Bateman, Randall J; Buckles, Virginia D.

Brain ; 145(10): 3594-3607, 2022 10 21.

Artículo Inglés | MEDLINE | ID: mdl-35580594

18.

Acute sleep loss decreases CSF-to-blood clearance of Alzheimer's disease biomarkers.

Liu, Haiyan; Barthélemy, Nicolas R; Ovod, Vitaliy; Bollinger, James G; He, Yingxin; Chahin, Samir L; Androff, Brendan; Bateman, Randall J; Lucey, Brendan P.

Alzheimers Dement ; 19(7): 3055-3064, 2023 07.

Artículo Inglés | MEDLINE | ID: mdl-36695437

19.

Design and feasibility of an Alzheimer's disease blood test study in a diverse community-based population.

Li, Melody; Li, Yan; Schindler, Suzanne E; Yen, Daniel; Sutcliffe, Siobhan; Babulal, Ganesh M; Benzinger, Tammie L S; Lenze, Eric J; Bateman, Randall J.

Alzheimers Dement ; 19(12): 5387-5398, 2023 Dec.

Artículo Inglés | MEDLINE | ID: mdl-37204806

20.

Confounding factors of Alzheimer's disease plasma biomarkers and their impact on clinical performance.

Pichet Binette, Alexa; Janelidze, Shorena; Cullen, Nicholas; Dage, Jeffrey L; Bateman, Randall J; Zetterberg, Henrik; Blennow, Kaj; Stomrud, Erik; Mattsson-Carlgren, Niklas; Hansson, Oskar.

Alzheimers Dement ; 19(4): 1403-1414, 2023 04.

Artículo Inglés | MEDLINE | ID: mdl-36152307

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